Mock Test Set- 14

Mock Test Set- 14

Q1. Which of the following features is most critical for identifying individual bitemarks in forensic analysis?

a) Shape of the dental arch

b) Presence of diastema

c) Rotational anomalies of teeth

d) Intercanine distance

Answer: c) Rotational anomalies of teeth

Explanation: Rotational anomalies provide unique identifiers due to the specific orientation of teeth in an individual's dental arch.

Q2. Which statistical method is used to compare toolmarks quantitatively?

a) Bayesian inference

b) ANOVA analysis

c) Random forest analysis

d) Cross-correlation analysis

Answer: d) Cross-correlation analysis

Explanation: Cross-correlation is used to measure the similarity between two sets of toolmark striations.

Q3. Which factor is critical for preventing cross-reactivity in immunoassays?

a) pH of the buffer

b) Choice of antibodies

c) Enzyme concentration

d) Temperature

Answer: b) Choice of antibodies

Explanation: Antibodies with high specificity minimize cross-reactivity.

Q4. Which buffer is commonly used in DNA electrophoresis?

a) Tris-acetate-EDTA (TAE)

b) Tris-HCl buffer

c) Phosphate-buffered saline (PBS)

d) Tris-glycine buffer

Answer: a) Tris-acetate-EDTA (TAE)

Explanation: TAE buffer maintains pH stability and ensures efficient DNA migration.

Q5. Which dye is commonly used to visualize DNA in electrophoresis?

a) Ethidium bromide

b) Coomassie blue

c) Bromophenol blue

d) Crystal violet

Answer: a) Ethidium bromide

Explanation: Ethidium bromide intercalates into DNA and fluoresces under UV light, aiding visualization.

Q6. The Controlled Substances Act (CSA) classifies drugs based on their:

a) Legal status

b) Chemical structure

c) Potential for abuse and medical use

d) Toxicity levels

Answer: c) Potential for abuse and medical use

Explanation: The CSA categorizes substances into schedules based on their abuse potential and medical utility.

Q7. What is the primary metabolite of heroin detected in biological samples?

a) Morphine

b) Codeine

c) 6-Monoacetylmorphine (6-MAM)

d) Methadone

Answer: c) 6-Monoacetylmorphine (6-MAM)

Explanation: 6-MAM is a unique metabolite of heroin, indicating heroin use.

Q8. What is the primary mechanism of action of opiates on the central nervous system?

a) Inhibition of serotonin reuptake

b) Stimulation of GABA receptors

c) Activation of opioid receptors

d) Inhibition of acetylcholine release

Answer: c) Activation of opioid receptors

Explanation: Opiates bind to opioid receptors, reducing pain signals and inducing sedation.

Q9. Which enzyme is responsible for the metabolism of codeine to morphine in the liver?

a) CYP2D6

b) CYP3A4

c) CYP1A2

d) UGT1A1

Answer: a) CYP2D6

Explanation: Codeine is metabolized to morphine by the cytochrome P450 enzyme CYP2D6.

Q10. What is the most common method of administering naloxone to reverse opioid overdose?

a) Oral

b) Intravenous

c) Subcutaneous

d) Intramuscular

Answer: b) Intravenous

Explanation: Intravenous administration of naloxone provides the fastest reversal of opioid effects.

Author:- Srishti Dutta