Biological Sciences_Part-2_FACT 2018_Previous Year Question Paper

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 Q.36 Cephalic index is used to identify

A.      Age

B.      Sex

C.      Race

D.     Stature

ANSWER: C

Q.37 From which part of cinchona plant, a drug is obtained

A.      Flower

B.      Leaf

C.      Bark

D.     Root

ANSWER: C

Cinchona officinalis

• A medicinal plant, its species used for the production of quinine(anti-fever agent).
• It is especially useful for treatment of malaria.
• Alkaloids:- cinchonine, cinchonidine and quinidine

Q.38 Pigment granules, cortical fusi, ovoid bodies are present in which part of hair

A.      Scales

B.      Cuticle

C.      Cortex

D.     Medulla

ANSWER: C

Q.39 Which of the following is NOT a natural fiber

A.      Jute

B.      Silk

C.      Rayon

D.     Ramie

ANSWER: C

Jute	bark of the white jute plant (Corchorus capsularis) and to a lesser extent from tossa jute (C. olitorius). It is a natural fibre with golden and silky shine and hence called the Golden Fibre.
Silk	the cocoons of the larvae of the mulberry silkworm (Bombyx mori)
Ramie	A bast fibre(collected from the phloem) extracted from the inner bark (phloem) of the ramie plant (Boehmeria nivea) also called China grass.

 Q.40 Which of these fibers are obtained from leaf of its plant

A.      Cotton

B.      Coir

C.      Hemp

D.     Abaca

ANSWER: D

Cotton	plant seed hairs
Coir	husk of the coconut
Hemp	seed hairs; derived from the hemp plant under the species of Cannabis. One of the strong member of bast fiber.
Flax	Stem/bast fibres
Sisal	leaf fibres
Abaca	Musa textilis(plant) leaf stalks (petioles)

 Q.41 Difference in the number of base pairs of the Amelogenin gene between X and Y chromosome is

A.      14

B.      20

C.      6

D.     4

ANSWER: C

Amelogenin (AMEL) gene

• Exists on both X and Y chromosomes.
• Used to determine the gender in cattle and humans.
• Amelogenin (AMEL) locus encodes a matrix protein forming tooth enamel. Mutations in the AMEL locus can lead to the enamel defect known as amelogenesis imperfecta, which results in the abnormal formation of tooth enamel

Q.42 Watson and Crick received Nobel prize for their work in the year

A.      1953

B.      1955

C.      1962

D.     1980

ANSWER: C

The Nobel Prize in Physiology or Medicine in 1962 was awarded to James Watson, Francis Crick and Maurice Wilkins for their discovery of the molecular structure of DNA, which helped solve one of the most important of all biological riddles.

 Q.43 Most commonly used STR loci in Forensic DNA profiling are

A.      Dimeric

B.      Trimeric

C.      Tetrameric

D.     Pentameric

ANSWER: C

 Q.44 According to the current concept death is defined as:

A.      Irreversible cessation of all vital functions of body

B.      Irreversible stoppage of brain stem functions

Irreversible stoppage of Lung functions

D.     Irreversible cessation of function of Heart

ANSWER: B

 Q.45 Which of the following injury is NOT possible by blunt forces

A.      Incised

B.      Abrasion

C.      Bruise

D.     Laceration

ANSWER: A

 Q.46 Kicking by a shoe sole produces

A.      Scratch abrasion

B.      Graze abrasion

C.      Patterned abrasion

D.     Incised wound

ANSWER: C

Q.47 Who is NOT associated with the ultra structure of cell membrane

A.      Overton

B.      Gorter and F. Grendel

C.      Robertson

D.     Robert Hooke

ANSWER: D

 Q.48 BLOSSUM matrices are used for

A.      Multiple sequence alignment

B.      Pairwise alignment

C.      Phylogenetic analysis

D.     All of the options

ANSWER: B

• In bioinformatics, the BLOSUM matrix (BLOcks SUbstitution Matrix) is a substitution matrix used for sequence alignment of proteins.
• BLOSUM matrices are used to score alignments between evolutionarily divergent protein sequences.
• They are based on local alignments.

 Q.49 The computational methodology that tries to find the best matching ligand is

A.      Molecular matching

B.      Molecular docking

C.      Molecular affinity checking

D.     Molecular fitting  

ANSWER: B

Matched molecular pair analysis (MMPA)

A method in cheminformatics that compares the properties of two molecules that differ only by a single chemical transformation, such as the substitution of a hydrogen atom by a chlorine one.

Molecular docking

A key tool in structural molecular biology and computer-assisted drug design. The goal of ligand-protein docking is to predict the predominant binding mode(s) of a ligand with a protein of known three-dimensional structure.

Molecular dynamics flexible fitting (MDFF)

A method used to flexibly fit atomic structures into density maps. The method consists of adding external forces proportional to the gradient of the density map into a molecular dynamics (MD) simulation of the atomic structure.

Q.50 GRAIL is acronym of

A.      Gene relationship across implicated loci

B.      Genetic rule around inbred loci

C.      Genomic revolution across indigenous loci

D.     Genetic revolution across Indian Land

ANSWER: A

Gene Relationships Across Implicated Loci (GRAIL) is a free web application developed by Soumya Raychaudhuri at the Broad Institute with the goal of determining the relationships among genes in different disease associated loci through statistical analysis.

Q.51 Central Dogma of Molecular Biology was first stated by

A.      Watson and Crick

B.      Beedal and Tatum

C.      Klug

D.     Crick

ANSWER: D

Q.52 Gustafson’s contribution to forensic science is

A.      Estimation of age from teeth

B.      Estimation of time since death due to fire

C.      Estimation of time since death in drowning

D.     Estimation of age from Xray of hand

ANSWER: A

Q.53 Basi-sphenoid suture in skull is used for determining

A.      Species of origin

B.      Estimation of age

C.      Estimation of height

D.     Sex determination

ANSWER: B  

Q.54 Acromion process is present in

A.      Fibula 

B.   Pelvis

C.      Scapula

D.     Humerus

ANSWER: C

Q.55 Eruption of permanent maxillary canine tooth in humans happens between

A.      5-6 years

B.      11-12 years

C.      8-9 years

D.     14-15 years

ANSWER: B

 Q56 One of the method to estimate age from bone is

A.      Osteon counting

B.      Colouring of bones due to age

C.      Examination of colour of bone marrow

D.     Measuring with osteometric board

ANSWER: A

• Osteons are the basic functional unit of compact bone.
• Osteons are made of many concentric lamellae (layers) that are similar to rings of a tree.
• These layers are made of mainly osteocytes (bone generating cells) and branch out from the central canal.
• Osteons in a bone fragment can be used to determine the sex of an individual and age, as well as aspects of taxonomy, diet, health and motor history.

 Q.57 Xiphoid process is

A.      Portion of sternum

B.      Portion of scapula

C.      Portion of coccyx

D.     Portion of condyle

ANSWER: A

 58 Symphysial face of pubis is helpful to find out

A.      Sex from pelvis

B.      Age from pelvis

C.      Deterioration of bony material with age

D.     Stature from pelvis

ANSWER: B

59 Supra-orbital ridges are related to

A.      Injury during life time

B.      Estimation of age

C.      Determination of sex

D.     Deterioration of bone

ANSWER: C

 60 Primary dentition starts with

A.      Mandibular central incisor

B.      Maxillary central incisor

C.      Lower lateral incisor

D.     Upper lateral incisor

ANSWER: A

Q.61 Blood groups antigens A and B are related to

A.      Plasma

B.      Platelets

C.      WBC

D.     RBC

ANSWER: D

62 Rh antigen was described by

A.      Landsteiner and Levine

B.      Landsteiner and Wiener

C.      Weiner and Levine

D.     Davidsohn and Wiener

ANSWER: B

ABO blood group system	Karl Landsteiner in 1901
MN blood group system	Karl Landsteiner and Philip Levine in 1927
Rh blood group system	Karl Landsteiner and A.S. Weiner in 1940
Bombay Blood Group	1952 by Dr Y M Bhende

 63 Acetone chlor-hemin test was recommended by

A.      Takayama

B.      Wagenaar

C.      Teichman

D.     Barberios

ANSWER: B

Presumptive test for blood

Wagenaar test

Sample + acetone + drop of HCL = Dark brown multi shaped crystals

Teichman test (Heamatin crystal test)

Sample + glacial acetic acid + NaCl =  Brown rhombic crystals

Takayama test (Hemochromogen test)

Sample + saturated glucose solution + NaOH (10%) + Pyridine = pink feathery crystals

 Q.64 HLA locus is located on

A.      Long arm of chromosome 6

B.      Short arm of chromosome 6

C.      Long arm of chromosome 4

D.     Short arm of chromosome 4

ANSWER: B

Human leukocyte antigen (HLA) super-locus is a genomic region in the chromosomal position 6p21 that encodes the six classical transplantation HLA genes and at least 132 protein coding genes

 65 Tamm-Horsfall glycoprotein is found in

A.      Urine

B.      Saliva

C.      Vaginal secretion

D.     Sweat

ANSWER: A

Tamm-Horsfall glycoprotein also called uromodulin.

 66 Ossification of bones help in estimation of

A.      Sex

B.      Age

C.      Race

D.     Stature

ANSWER: B

  67 Which is useful in estimation of age of an individual at the time of death

A.      Facial reconstruction

B.      Adipocere

C.      Skull-photo superimposition

D.     Epiphyseal union

ANSWER: D

 68 Which does NOT relate to diatoms

A.      Frustules

B.      Epitheca

C.      Cingulum

D.     Colpus

ANSWER: D

 69 Which was the first PCR based DNA marker

A.      THO1

B.      D16S539

C.      D10S28

D.     HLA-DQA1

ANSWER: D

 70 Bombay blood groups are devoid of

A.      A antigen only

B.      B antigen only

C.      A and B antigen only

D.     A, B and H antigen

ANSWER: D

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